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Over time, the dosage is gradually increased, depending on how your body responds

10.1016/0140-6736(91)92978-B Lancet 19 DevosD.MoreauC.DevedjianJ

doi: 10.1021/ja075261o

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Epidermal mechanical scratching-induced ROS exacerbates the itch-scratch cycle through TRPA1 activation on mast cells in atopic dermatitis

Agree that, without randomization, the data raise as many questions as they answerparticularly around patient selection, persistence, and unmeasured confounding